METFORMIN
453 Replies
cheri - March 19

~alex~ how are you? your ovulating and that is good! You soungda little discouraged, thats how I feel too, I wish I can just sit with my dr and ask all the questions that I have going thru my head right now, there are alot of success stories I have heared so I havent gave up, and I hope u havent either good luck!!!!!!!

 

Anna - March 20

Hi all..I have been through one iui (unsucessful) one year of clomid and metformin (unsucessful) and now I am on Metformin alone. My fiance thinks i will never have kids of my own...i think Metformin will enable this (I am keeping faith)...I pray for all of you...because I know how difficult this is ...not every month but every living minute...Good Luck everyone...

 

Alex - March 22

Hi all. My cousin called me yesterday and told me she is pregnant. It is a reminder that I dont work. Does anyone else feel low when friends tell them they are pregnant. I have about 6 weeks left on Metformin then back to the Dr. What happens then? Will they try Chlomid, or the mix f Metformin and Chlomid? Great news though... Me and hubby move into our new home tomorrow. x x x

 

~cheri~ - March 22

Alwx~ I know how you feel, you feel happy for your friends but yet sad cause you would love to be pregnant. You know what makes me so angry is that I have a friend that is pregnant and she drinks and done drugs and now shes started to stop bcuz shes 7months! Im over here trying so hard to get pg and shes like tring to lose hers! but I know how u feel Alex. I feel really discouraged I dont want give up and hate playing the waiting game! but god bless and keep the faith. And one one thing to EVERYONE I called the e.p.t p test number and it said clomiphine and ovarian cysts CAN affect the results of the pg (can make it inaccurate) and other stuff so keep note~ baby dust

 

yasmin - March 26

well i been on met for about a week now and i was wondering when u conceive will i have a chance in becoming preg with twins or triplets

 

Cheri - March 26

Yasmin: Unless you have twins in your family I dont think so. Metformin wont cause twin or triplets its more of the fertility drugs that usually do. I had the same concern and my doctor said this medicine wont cause it. Good luck tho how long have u been trying?

 

JULIA Pelish - April 3

hi my name is julia and i have psos. sory just trying to keep a sence of humor with all of this. i was just put on metformin about o months ago. i was having very strage periods. where some times i would go months at a time with out having one then i would have continuous periods for a month or so strait. i got realy worried after the second time my period continued for so long. i really didn't even know that i had a problem till my doctor told me i probably wasn't ovulating and i started crying in her office. i just thought i hadn't been trying at the right times. i mean we weren't realy trying to get pregnant just basically sayig if it happened it would be great. but after three years of not using protection and nothing happening and now learning that the whole time i was not ovulating i guess it got me realy upset. my dr. gave me progesterin to help me with my period the first month and ence then 40 days later i am now having anouther period with =out the help of projesterin so i guess the metformin is doing something. i'm going to a fertility specialist on the 5th to make sure there isn't anything else in my way as far as getting pregnant. i just stumble across this web site looking to make sure if i got pregnant ther would't be any side affects to taking metformin. i hope you all know how much seeing that i was not alone helped me so much. i started crying again. this time happy tears of hope. i hope it happens for me and all of you out there wanting to get pregnant too. if any one wants to keep in touch with each other i just found this great web site called myspace.com and it makes talking and sharing information easy. my name on there is pandorah7777. just in case you need some one to talk to. thanks again.

 

JULIA Pelish - April 3

hey just found this on a web site. the web address is....
http://www.ovarian-cysts-pcos.
com/glucophage-metformin-pcos.html
it
was what i was looking for when i stumbled across this web site and all of you wich i am so glad i did. i know there were a lot of questions in this regard so i thought i would post it.


VITAMIN B12 MALABSORPTION. Of patients who take this drug, 10%-30% show evidence of reduced vitamin B12 absorption. A substance formed in the stomach called "intrinsic factor" combines with B12 so that it can be transferred into the blood. Metformin interferes with the ability of your cells to absorb this intrinsic factor-vitamin B12 complex.(12)

Over the long term, vitamin B12 insufficiency is a significant health risk. B12 is essential to the proper growth and function of every cell in your body. It's required for synthesis of DNA and for many crucial biochemical functions. There is also a link between B12 insufficiency and cardiovascular disease.

At least one study raises the concern that even if metformin is withdrawn, the vitamin B12 malabsorption may continue in some people.(13) The apparent cause is continued problems with availability of intrinsic factor, which is required for B12 absorption.

ELEVATED HOMOCYSTEINE. People who take Glucophage tend to have higher homocysteine levels.(14) Women with PCOS also tend to have elevated homocysteine.(15)

Homocysteine is an amino acid in the blood. A normal amount is OK. But an elevated level means that your metabolic processes are not working properly. Elevated homocysteine is associated with coronary artery disease, heart attack, chronic fatigue, fibromyalgia,(16) cognitive impairment.(17), and cervical cancer. (18)

Vitamin B12, along with vitamin B6 and folic acid (another B vitamin), is responsible for metabolizing homocysteine into less potentially harmful substances (19). Therefore, when metformin reduces absorption of vitamin B12, you lose one of the nutrients needed to reduce homocysteine and thus reduce your risk of cardiovascular disease.
ELEVATED HOMOCYSTEINE & PREGNANCY COMPLICATIONS. Pre-eclampsia is a complication of pregnancy characterized by increasing blood pressure and edema. If left untreated, pre-ecampsia can lead to eclampsia, a serious condition that puts you and your baby at risk. In a study conducted at the Center for Perinatal Studies at Swedish Medical Center in Seattle, a second trimester elevation of homocysteine was associated with a 3.2 fold increased risk of pre-eclampsia.(20)

The Dept. of Obstetrics and Gynecology, Nijmegen, The Netherlands, reviewed a series of studies on the linkage between elevated homocysteine and early pregnancy loss. They concluded that high homocysteine levels are a risk factor for recurrent early pregnancy loss.(21)

Ovarian follicular fluid contains detectable amounts of homocysteine along with B12, B6, and folic acid. The follicular fluid provides nourishment to the egg by facilitating transport of nutrients from blood plasma. High levels of homocysteine as well as an insufficiency of B vitamins may adversely influence the process of fertilization and early fetal development.(22)

NOTE: We are suggesting that elevated homocysteine, not metformin itself, could contribute to pregnancy complications in some women. However, metformin does contribute to increased homocysteine levels.

PREGNANCY WARNING. Many women use metformin in their pursuit of a successful pregnancy. However, Glucophage is a category B drug, meaning its safety for use while pregnant has not been established. It is found in breast milk so it's not advisable to breast feed while taking Glucophage.

 

julied - April 4

2 weeks now and nothing yet...im positive though it makes me feel like i have the flu.

 

nicci - April 6

i have been on metformin for four months mow. my doc says it could take up to six months to regulate my cycles, then i will be able to start trying to get pregnant.

 

marcie - April 7

i have been on metform since 10/2005 w/ birth control then he told me to stop taking the birthcontrol in dec so i did..i had a period in jan but none since i took a preg test 1 month ago and it was neg do you think this will work for me i have had pcos since i was 13 thats when the periods got wacky?

 

DebbAlvarez - April 8

Hi all! I'm Debb, 27, married, ttc w/ pcos. I was diagnosed with pcos about 7 years ago and have yet to ever get pregnant. In the past I did only one round of clomid, however, it didn't work. I tried telling myself, it will happen in God's timing for years. My husband and I have prayed and prayed to have a baby. Now my feeling has changed. I believe God gives us all a brain, so I have to use it. God has given these Dr's and scientist the intelligence to make these drugs to increase our chances of pregnancy, so rely on them. :) It seems like for a long time now the only time I ever even have my period is when I take provera to induce it. Well, this time I took provera to induce it again and I'm on CD3. I started taking Metformin last night. 500mg 1x a day for the first week, 500mg 2x a day 2nd week, 3x for the 3rd week. I'm also taking ovulex, haven't heard as many success stories on it as I have on metformin, but it does supposed to help you ovulate longer, so we'll see. I guess I'm going to buy an ovulation prediction kit to help me know when I ovulate. My question is, does it help that my husband and I have a very healthy sex life? Meaning we engage in adult behavior (HA!HA!) every day (sometimes more than once a day) or at least every other day? Will this help to increase our chances of making sure we have sex at the right time during ovulation? I feel so lost and helpless with all this..... I've also started charting btw. Well, I hope it's ok that I join the chat. Good luck and God Bless to everyone!

 

aessem - May 3

Hello everyone. I'm so glad I found this website. I first got my period when I was 13, it was terrible. I then went a year with out it and then it was terrible. I continued this yearly cycle till I was 16 and my mother feared I was following in her foot steps of PCOS & endometrosis. I was put on birthcontrol until I was 18 and this helped greatly I always got a monthly cycle and it wasn't that heavy or painful. After I stoped the birth control I got one cycle right away and then never again so I went to my gyno and he insisted I needed the birthcontrol, he never tested me for PCOS. So I went to a endocynologist who ran blood work and confirmed I had PCOS and put me on metformin. I started metformin June of 2005, I had a cycle right away and then not till Nov 2005 then in Feb 2006 (only one day) and then April 2006 for two weeks, during which I went in for lyposcopy to see if I had endometriosis (having extreme pains in left ovary area). Its been confirmed I have both enlarged ovaries and insuline resistance (PCOS) & dirfuse endometriosis. My endo wanted to put me into a false menophase to stop the endo growth but I refused and insisted I would try for pregnancy. We have been trying since April 15 and recently I have been getting headaches, dizzy, nausea, and sensistive to smells. I have wondered if I could be pg but I thought it would be harder. I haven't taken a pg test for the fear of finding out it is neg. I also don't know when I should take on for I don't know if my period will be normal or not this month. Any suggestion would be great.

 

Alex - May 28

Hi all. sorry not been here for ages, just moved and had no internet access. Hope you are all ok. I had an appointment with the gynea last week. I have been on Metformin for 6 months so she put me on Chlomid with the Metformin. Not had a period yet so haven't taken the chlomid which you take for 5 days from day 2. Has anyone used chlomid before? Did you have any side effects? lots of loveto you all. x

 

pm1307 - June 2

so if metformin is just a diabetic drug, then why do we use it? imy insulin levels are fine, and my doctor is going to put me on provera then metformin, and she told me that metformin will hrelp me ovulate and a chance of more than one? was she lieing? im so confused on all these drugs, she sadi hopefully we'll get PG when im on metformin and if not she'll strat me on clomid. just waiting for the blood tests to come back, she's allso checking for PG havent's had my AF since 3/10 and then 16 days later i spotted for 2 days and nothing since then.

 

Lynn - June 4

hi, just letting you know to trust and follow your doctor. I was put on metformin October of 05 after ectopic surgery. There is also nothing wrong with my insulin levels and it is to aide in ovulation. I am PCOS so do not ovulate on my own without metformin. I am alos missing a right fallopian tube since my surgery. I have taken clomid (bad side effects for me) with nothing. I did some injections and nothing. We took a break from infertility world and decided we would focus on us. My dh decided we need to BD for 3 weeks beginning after AF left. We did...every week we BD 5 out of 7 days and I am happy to say I am 4 weeks and 2 days pregnant. Take metformin if your stomach can handle it (some cannot). I have been on it for 7 months tomorrow. As for clomid, I had HUGE mood swings on it. It was bad, so bad I dislike myself. So, be careful taking it and if you notice anything funny, ask about femera.

 

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